Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.218.1-218.1
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- 2003
Chemopreventive Allylthiopyridazines, K compounds, Inhibit Invasion, Migration and Angiogenesis in SK-Hep-1 Hepatocarcinoma Cells Possibly via MMP-2 Downregulation
- Lee, Eun-Jung (College of Pharmacy, Duksung Women′s University) ;
- Shin, Ilc-Hung (College of Pharmacy, Duksung Women′s University) ;
- Kwon, Soon-Kyung (College of Pharmacy, Duksung Women′s University)
- Published : 2003.04.01
Abstract
Dietary organosulfur compounds have been shown to inhibit the proliferation of tumor cells. Synthetic sulfur-containing compounds including oltipraz exert chemopreventive and hepatoprotective effects. We previously showed that synthetic allylthiopyridazine derivatives designated as K compounds induced apoptosis in SK-Hep-1 hepatocarcinoma cells (Eur. J. Cancer: 37, 2104-10, 2001). (omitted)
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