Effects of Age, Brain-regional Selectivity, and Ovariectomy on Sexual Dimorphism of Organophosphate Pesticide Terbufos

  • Kim, Seung-Yong (Toxicology Lab., Korea Institute of Science and Technology, Department of Biology, Kyunghee University) ;
  • KimKwon, Yun-Hee (Department of Biology, Kyunghee University) ;
  • Kwon, Oh-Seung (Toxicology Lab., Korea Institute of Science and Technology)
  • Published : 2003.04.01

Abstract

A sexual dimorphism in terbufos (S-t-butylthiomethyl-O,O-diethyl phosphorodithioate: TBF) toxicity was not reported and remains unclear. Previously. we reported that TBF treatment showed sexual dimorphic effects on acetylcholinesterase (AchE) activity. We further investigated that sexual dimorphism of TBF was affected to age and brain-regional selectivity, and whether ovary plays an important role in the effect. (omitted)

Keywords