PAH regualtion of CYP1 gene in MCF-7 & ZR-75-1 human breast cancer cells

  • Published : 2003.04.01

Abstract

Recent industrial society has human widely exposed to PAHs that are comming from the incomplete combustion of organic material as widerspread environmetal contaminants. Biological activities of PAHs are not known although PAHs are considered as carcinogens. The mechanism of action of PAHs has been studied extensively, however it is not clear how PAHs turn on CYP1A1 in human breast cancer. (omitted)

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