Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Chemopreventive Effect of Retinoids on Cellular NF-kappaB Activity Induced by Alkylating Carcinogens in Human Epidermal Keratinocytes

  • Cho, Eun-Jeong (Department of Clinical Pathology, and Bioindustry＆Technology Research Institute, Kwangju Health College) ;
  • Lee, Min-Hee (Department of Clinical Pathology, and Bioindustry＆Technology Research Institute, Kwangju Health Colleg) ;
  • Kim, Seung-Kyoon (Department of Clinical Pathology, and Bioindustry＆Technology Research Institute, Kwangju Health Colleg) ;
  • Lee, Young-Jong (Department of Clinical Pathology, and Bioindustry＆Technology Research Institute, Kwangju Health Colleg) ;
  • Moon, Ki-Young (Department of Clinical Pathology, and Bioindustry＆Technology Research Institute, Kwangju Health College)
  • Published : 2003.04.01
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Abstract

Retinoids have been shown to be effective in suppressing tumor development in chemical carcinogens such as N-nitroso-N-methylurea (NMU) and N-nitroso-N-ethylurea (NEU) induced mammary tumors in various animals. However, retinoids-mediated chemopreventive process, linked to transcription factor NF-kappaB activation on chemoprevention has yet to be studied. (omitted)

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