Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Regulatory Effect of Atopic Allergic Reaction by Pachydictyon coriaceum

  • Na, Ho-Jeong (Department of Oriental Pharmacy, Wonkwang University) ;
  • Moon, Phil-Dong (Division of Ocean Science, Korea Maritime University) ;
  • Hong, Seung-Heon (Division of Ocean Science, Korea Maritime University) ;
  • Seo, Young-Wan (Division of Ocean Science, Korea Maritime University) ;
  • Kim, Hyung-Min (Division of Ocean Science, Korea Maritime University)
  • Published : 2003.04.01
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Abstract

We studied the effect of methanol extract of Pachydictyon coriaceum (PC) on atopic allergic reaction. PC dose-dependently inhibited interleukin (IL)-8 and tumor necrosis factor (TNF)-$\alpha$ secretion from the PMA- pius A23187- stimulated HMC-1. PC also dose-dependently inhibited the histamine and $\beta$-hexosaminidase release from mast cells. PC had no cytotoxic effect. (omitted)

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