대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
- /
- Pages.125.2-126
- /
- 2003
High Throughput Fluorogenic Assay for TNF-alpha Converting Enzyme(TACE) inhibitors
- Keum, Se-Hoon (New Drug Research Center, Yuhan Research Institute) ;
- Lee, Bong-Yong (New Drug Research Center, Yuhan Research Institute)
- 발행 : 2003.04.01
초록
Human tumor necrosis factor-alpha (TNFa) is a key pro-inflammatory cytokine produced by activated monocytes and macrophage as a part of the self-defence machinery. TNF-a converting enzyme (TACE) is the metalloproteinase that processes the membrane bound precursor of TNFa to the soluble component. (omitted)
키워드