대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.121-121
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- 2003
Enhanced mucosal and systemic immune responses by mucosally administered hepatitis B surface antigen: effects of vaccine delivery vehicles and adjuvants
- Park, Jeong-Sook (College of Pharmacy, Seoul National University) ;
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Kim, Chong-Kook
(College of Pharmacy, Seoul National University)
- 발행 : 2003.04.01
초록
The purpose of this study is to investigate the effect of mucosal vaccine delivery vehicles and adjuvants on the local and systemic antibody responses following mucosal immunization of mice with hepatitis B surface antigen (HBsAg). Mice were immunized on days 0 and 21 by administration of hepatitis B surface antigen B (HBsAg) into the vagina. HBsAg was delivered in saline or poloxamer(Pol)-based vehicle containing mucoadhesive polycarbophil (PC). (omitted)
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