Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10a
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- Pages.102-103
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- 2003
Transcriptional Induction of Cyclooxygenase-2 in Osteoclast Precursors is Involved in TRANCE-induced Osteoclastogenesis
- Han, Song-Yi (Division of Molecular Life Sciences and Center for Cell Signaling Research, Ewha Womans University) ;
- Lee, Na-Kyung (Division of Molecular Life Sciences and Center for Cell Signaling Research, Ewha Womans University) ;
- Kim, Kyung-Hee (Division of Molecular Life Sciences and Center for Cell Signaling Research, Ewha Womans University) ;
- Lee, Soo-Young (Division of Molecular Life Sciences and Center for Cell Signaling Research, Ewha Womans University)
- Published : 2003.10.01
Abstract
Osteoclast are specialized cells derived from the monocyte/macrophage haematopoietic lineage that develop and adhere to bone matrix, then secrete acid and lytic enzymes that degrade it in a specialized, extracellular compartment. Regulation of osteoclast differentiation is central to the understanding of the pathogenesis and treatment of bone diseases such as osteoporosis. (omitted)
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