Proceedings of the Korean Society of Sericultural Science Conference (한국잠사학회:학술대회논문집)
- 2003.10a
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- Pages.112-113
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- 2003
Kynurenic Acid (KYNA) Attenuates Oxidative Stress and Mitochondrial damage in 6-OHDA-induced Dopaminergic Neuronal Cell Death
- Lee, Hyun-Jung (Chung Ang University) ;
- Joo, Wan-Seok (BioGrand Inc) ;
- Yeo, Joo-Hong (Rural Development Administratio) ;
- Lee, Kwang-Gill (Rural Development Administratio) ;
- Chae, Hee-Sun (Chung Ang University) ;
- Kang, Yong-Koo (BioGrand Inc) ;
- Lee, In-Sook (BioGrand Inc) ;
- Kweon, Hae-Yong (Rural Development Administratio) ;
- Lee, Ang-Hyung (BioGrand Inc.) ;
- Kim, Sung-Su (Chung Ang University)
- Published : 2003.10.01
Abstract
Kynurenic acid (KYNA), tryptophan metabolite is known to have cell protective effect against various insults in the brain. But so far, the protective mechanism is largely unknown. In this study, we investigated how the KYNA exerts protective effect against 6-OHDA, a causative molecule of Parkinsonian syndrome, using SH-SY5Y cells. (omitted)
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