Molecular Cloning of a cDNA Encoding Putative Apolipophorin III from the Silkworm, Bombyx mori

  • Yun, Eun-Young (Department of Sericulture and Entomology, The National Institute of Agricultural Science and Technology, RDA) ;
  • Goo, Tae-Won (Department of Sericulture and Entomology, The National Institute of Agricultural Science and Technology, RD) ;
  • Kim, Sung-Wan (Department of Sericulture and Entomology, The National Institute of Agricultural Science and Technology, RD) ;
  • Hwang, Jae-Sam (Department of Sericulture and Entomology, The National Institute of Agricultural Science and Technology, RD) ;
  • Kwon, O-Yu (Department of Anatomy, College of Medicine, Chungnam National University) ;
  • Kang, Seok-Woo (Department of Sericulture and Entomology, The National Institute of Agricultural Science and Technology, RDA)
  • 발행 : 2003.10.01

초록

Apolipophorin III (apoLp-III) is a protypical exchangeable apolipoprotein that is abundant in hemolymph of many insect species. Its function lies in the stabilization of low-density lipophorin particles (LDLp) crossing the hemocoel in phases of high energy consumption to deliver lipids from the fat body to the flight muscle cells. But, recent studies with naive Galleria mellonella-apoLp-III gave first indications of an unexpected role of that protein in insect immune activation (Niere et al., 1999). (omitted)

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