Characterization of antihypertensive effect of Isaria sinclairii and its Genotoxic evaluation in 3 sets of mutagenicity tests

  • Ahn, Mi-Young (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA) ;
  • Ryu, Kang-Sun (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RD) ;
  • Kim, Iksoo (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RD) ;
  • Kim, Jin-Won (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RD) ;
  • Lee, Yong-Ki (Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA)
  • 발행 : 2003.04.01

초록

The present study examined the effect of alcohol extract of Isaria sinclairii on blood pressure in spontaneously hypertensive rats (SHR). The blood pressure and heart rate were measured after treatment of alcohol extract of I. sinclairii by indirect tail cuff method and direct tn vivo model. Male SHR were treated with extracts for 2 or 4 weeks starting at 12 weeks of age. (omitted)

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