한국수의병리학회:학술대회논문집 (Proceedings of the Korean Society of Veterinary Pathology Conference)
- 한국수의병리학회 2003년도 추계학술대회초록집
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- Pages.54-54
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- 2003
Malignant Inflammatory Fibrous Histiocytoma in a Pointer Dog
- Do, Sun-hee (Dept. of Vet. Pathol., College of Vet. Med., Kyungpook National Univ.) ;
- Jeong, Kyu-shik (Dept. of Vet. Pathol., College of Vet. Med., Kyungpook National Univ.)
- 발행 : 2003.10.01
초록
Malignant fibrous histiocytomas (MFHs) is the most common type of soft tissue sarcoma in the old animal with a aggressiveness, a high local recurrence rate and significant metastatic rate, which associated with a poor prognosis. In most histologic and immunohistological studies, the tumor cells raised from a fibroblastic and/or myofibroblastic phenotype, presumably from undifferentiated mesenchymal cell origin. MFHs are usually firm and invasive, arising in the subcutis; metastasis depends on tumor grade (many are grade 3) [1,2]. The primary tumor cells are pleomorphic, varying in appearance from fusiform to round. Often nucleoli are prominent and irregular [5]. Extracellular amorphous eosinophilic material may be prominent and likely represents reactive collagen production by the tumor [5]. (omitted)
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