Induction of Reactive Oxygen Species and Malignant Transformation by Tcdd Through Metabolic Formation of Catechol Estrogens

  • 발행 : 2003.10.01

초록

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a prototype of halogenated aromatic hydrocarbons, is a persistent environmental contaminant and one of the most powerful tumor promoters. The molecular mechanism underlying induction of tumor promotion by TCDD has not been elucidated.(omitted)

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