Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.141-141
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- 2003
Activation of MKK6 Induces Invasive and Migrative Phenotypes in MCF10A Human Breast Epithelial Cells
- Song, Hyun (College of Pharmacy, Duksung Women′s University) ;
- Moon, Aree (College of Pharmacy, Duksung Women′s University)
- Published : 2003.10.01
Abstract
Ras expression has been suggested as a marker for tumor aggressiveness of breast cancer, including the degrees of invasion and tumor recurrence. We previously showed that p38 MAPK is a key signaling molecule differentially regulated by H-ras and N-ras, leading to H-ras-specific cell invasive and migrative phenotypes in human breast epithelial cells (Cancer Res.: 63, 5454-5461, 2003).(omitted)