13-Week Oral Gavage Toxicity with Sophora Japonica Linne Seed Extract in Sd Rats

  • Lee, Jae-Hyung (School of Life and Food Sciences, Handong University) ;
  • Kim, Il-Yong (School of Life and Food Sciences, Handong University) ;
  • Hyun, Chang-Kee (School of Life and Food Sciences, Handong University)
  • 발행 : 2003.10.01

초록

In recent years. attention has focused on the application of the alkaline single cell gel electrophoresis (SCGE or Comet) assay in environmental mutagenesis. To evaluate the suitability of the assay as a monitoring. technique, the DNA damages in liver cells and erythrocytes of carp (Cyprinus carpio) exposed to benzo[${\alpha}$]pyrene (B[${\alpha}$]P) were estimated comparatively with the in vivo Comet assay and the micronucleus test (MNT).(omitted)

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