Enhanced Prediction of Potential Rodent Carcinogenicity by Utilizing Comet Assay and Apoptotic Assay in Combination

  • Published : 2003.10.01

Abstract

The comet assay has been recently validated as a sensitive and specific test system for the quantification of DNA damage. with 11 substances that demonstrated positive results in at least one test among 4 standard short-term genotoxicity tests, and to evaluate its ability to predict rodent carcinogenicity.(omitted)

Keywords