한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2003년도 춘계학술대회 논문집
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- Pages.83-83
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- 2003
Mutational profiling of p53 gene in human breast epithelial cells (MCF10A) exposed to Benzo(a)pyrene(BaP) or N-Methyl-N'-nitro-N-nitrosoguanidine(MNNG)
- Kim, In-Sun (Division of Toxicology, College of Pharmacy, Sungkyunkwan University) ;
- Lee, Byung-Mu (Division of Toxicology, College of Pharmacy, Sungkyunkwan University)
- 발행 : 2003.05.01
초록
Mutations of p53 tumor suppressor gene have been associated with exposure to carcinogens. Cultured human breast epithelial cells (MCF10A) were treated with Benzo(a)pyrene(BaP) or N-Methyl-N'-nitro-N-nitrosoguanidine(MNNG). MCF10A cells were grown in DMEM/F12 medium and trated for 6, 12, 24, 48 and 96h with Bap (1, 10 and 100
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