한국독성학회:학술대회논문집 (Proceedings of the Korean Society of Toxicology Conference)
- 한국독성학회 2003년도 춘계학술대회 논문집
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- Pages.39-40
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- 2003
Strain-specific mammary tumor development following life-time oral administration of Ochratoxin A in DA and Lewis rats
- Son, Woo-Chan (Department of Veteinary Public Health, College of Veterinary Medicine, Seoul National University) ;
- Lee, Yong-Soon (Department of Veteinary Public Health, College of Veterinary Medicine, Seoul National University) ;
- Kang, Kyung-Sun (Department of Veteinary Public Health, College of Veterinary Medicine, Seoul National University)
- 발행 : 2003.05.01
초록
Ochratoxin A (OA), a potent nephrotoxin in several species, is knownto be a renal carcinogen in animals and is implicated in the etiology of Balkan endemic nephropathy (BEN). The NTP (National Toxicology Program) classified Ochratoxin A as having clear evidence of carcinogenic activity, based on uncommon tubular adenomas and tubular cell carcinomas of the kidney and multiple fibroadenomas of the mammary gland, seen in the rat.(omitted)