A stydy on the melanin synthesis inhibition of some natural plant extracts

  • Kim, W. H. (Drug Evaluation Department, Korea Food & Drug Administration) ;
  • K. H. Son (Drug Evaluation Department, Korea Food & Drug Administratio) ;
  • Lee, K. S. (Drug Evaluation Department, Korea Food & Drug Administratio) ;
  • W. J. Yang (Dept of Evaluation, korea advanced food institut) ;
  • E. H. Koh (Department of Chemistry, College of Natural Science, Duksung Wonen′s Universit) ;
  • Park, S. S. (Drug Evaluation Department, Korea Food & Drug Administration)
  • Published : 2003.09.01

Abstract

As melanin is a key material for skin pigmentation, inhibitors of melanin formation have been used to cosmetics and drugs to prevent hyperpigmentation. Therefore, search for effective inhibitor$ from various plants were attempted. For this purpose, I examined in vitro tyrosinase assay system. Tyrosinase showed a maximal activity at 4 units concentration of tyrosinase, 10 minutes, 42$^{\circ}C$ and pH 6.5.

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