대한화장품학회:학술대회논문집 (Proceedings of the SCSK Conference)
- 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
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- Pages.659-659
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- 2003
DA-3711:A POTENT TISSUE-ENGINEERED ACTIVE INGREDIENTS FOR ANTI-AGING
- Kim, B. M. ;
- Lee, M. ;
- Lee, J. H. ;
- I. S. Doo ;
- M. K. Son ;
- S. H. Kang ;
- Kim, W. B. ;
- J. W. Kwon
- 발행 : 2003.09.01
초록
In this study, we have investigated the potent anti-aging effect of DA-3711, a cosmetic ingredient derived from artificial skin culture. The artificial skin was originally developed as a skin replacement for the treatment of chronic skin wounds. To produce DA-3711, neonatal human fibroblasts were seeded into biocompatible collagen/chitosan/glycosaminoglycan (GAG) scaffolds and cultured in Dulbecco's modified Eagle's medium (DMEM) supplemented with fetal bovine serum and nonessential amino acids. Analysis of the culture broth (DA-3711) showed that growth factors such as VEGF, TGF-