Classification of C. elegans Behavioral Phenotypes Using Clustering

클러스터링을 이용한 C. elegans 행동표현형 분류

  • Nah, Won (School of Electronics, Telecommunications and Computer Engineering, Hankuk Aviation University) ;
  • Baek, Joong-Hwan (School of Electronics, Telecommunications and Computer Engineering, Hankuk Aviation University)
  • 나원 (한국항공대학교 전자, 정보통신,컴퓨터공학부) ;
  • 백중환 (한국항공대학교 전자, 정보통신,컴퓨터공학부)
  • Published : 2003.07.01

Abstract

C. elegans often used to study of function of gene, but it is difficult for human observation to distinguish the mutants of C. elegans. To solve this problem, the system, which can be classified automatically using the computer vision, is studying now. In the previous works , they described the auto-tracking system and the egg-laying timing modeling, which are used to automated-classily system. In this paper, we use three kinds of features, which are related to movement , size and posture of the worm, and each feature is described mathematically and normalized. In experimental result, we validated the features for the hierarchical clustering, And we used the Calinski and Harabasz's method to find the appropriate cluster number.

Keywords