Proceedings of the Korean Biophysical Society Conference (한국생물물리학회:학술대회논문집)

The Korean Biophysical Society (한국생물물리학회)
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Morphological and functional changes of dissociated single pancreatic acinar cells: testing the single cell as a model for exocytosis and calcium signaling

  • Lee, Misun (Department of Physiology, Sungkyunkwan University School of Medicine) ;
  • Uhm, Dae-Yong (Department of Physiology, Sungkyunkwan University School of Medicine) ;
  • Park, Myoung-Kyu (Department of Physiology, Sungkyunkwan University School of Medicine)
  • Published : 2003.06.01
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Abstract

Isolated single pancreatic acinar cells have long been used as a good model for studying many kinds of signaling processes due to their good structural and functional polarities without a significant validation. In this study, we have examined morphological and functional changes of the dissociated single pancreatic acinar cells by imaging cytosolic Ca$\^$2+/ concentration, exocytosis of granules, and by observing their shapes with confocal microscopy.

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