Proceedings of the Korea Society of Environmental Toocicology Conference (한국환경독성학회:학술대회논문집)
- 2003.05a
- /
- Pages.189-189
- /
- 2003
Kinetic behavior of sophoricoside by gas chromatography/mass spectrometry in rats
- Jeon, Hee-Kyung (Toxicology Laboratory, Korea Institute of Science & Technology) ;
- Park, Hae-Yeon (Toxicology Laboratory, Korea Institute of Science & Technology) ;
- Kim, Youn-Jung (Toxicology Laboratory, Korea Institute of Science & Technology) ;
- Kim, Youngsoo (College of Pharmacy, Chungbuk Natl. Univ.) ;
- Kim, Mi-Kyung (College of Medicine, Chungbuk Natl. Univ.) ;
- Lee, Seung-Ho (College of Pharmacy, Yeungnam Univ.) ;
- Jung, Sang-Hun (College of Pharmacy, Yeungnam Univ.) ;
- Ryu, Jae-Chun (Toxicology Laboratory, Korea Institute of Science & Technology)
- Published : 2003.05.01
Abstract
Sophoricoside was isolated as the inhibitor of IL-5 bioactivity from Sophora japonica (Leguminosae). To develope as novel anti-allergic drug, kinetic study was performed in rats. Serum concentration of sophoricoside was measured by gas chromatography-mass spectrometry (GC/MS) in male Sprague-Dawley rat (250
Keywords