Proceedings of the KSAR Conference (한국동물번식학회:학술대회논문집)
- 2003.06a
- /
- Pages.46-46
- /
- 2003
High-level Expression and Characterization of the Human Interleukin-10 in the Milk of Transgenic Mice
- Zneng, Z. Y. (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology) ;
- B. H. Sohn (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology) ;
- K. B. Oh (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology) ;
- W. J. Shin (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology) ;
- Y. M. Han (Department of Animal Resources Science, Chonbuk National University) ;
- Lee, K. K. (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology)
- Published : 2003.06.01
Abstract
Interleukin-10 (IL-10) is a homodimeric protein with a wide spectrum of anti-inflammatory and immune activities. It inhibits cytokine production and expression of immune surface molecules in various cell types. The transgenic mice carrying the human IL-10 gene in conjunction with the bovine