Proceedings of the Korean Society of Applied Pharmacology (한국응용약물학회:학술대회논문집)

The Korean Society of Applied Pharmacology (한국응용약물학회)
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Studies on the anti-coagulant component of Loranthus yadoriki

  • Lee, Sun-Kyung (Dept. of Molecular Medicine, Asan Institute for Life Sciences, College of Medicine, University of Ulsan) ;
  • Song, Hee-Sun (Dept. of Molecular Medicine, Asan Institute for Life Sciences, College of Medicine, University of Ulsan) ;
  • Yoo, Eun-A (Dept. of Chemistry, Sungshin Women′s University) ;
  • Yang, Hyun-Ok (Dept. of Anesthesiology & Pain Medicine, College of Medicine, University of Ulsan)
  • Published : 2003.11.01
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Abstract

Methanol extract of Loranthus yadoriki showed the prolongation effect of bleeding time in vivo using mice in dose dependent manner. From the MeOH extract of Loranthus yadoriki, compound-A was isolated by the activity guided isolation method using silicagel column chromatography. The anti-coagulant activity was evaluated by the bleeding time test in vivo and plasma recalcification time test in vitro. Compound A showed moderate anti -coagulant activity on plasma recalcification time in vitro.

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