대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.423.1-423.1
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- 2002
New Analytical Method of Cyclosporine A in Human Serum by High -performance Liquid Chromatography/Diode Array Detector and Its Application to Pharmacokinetics of Cyclosporine A in Human Volunteers
- Kim, Eun-Young (Loxicology Lab., Korea Institute of Science and Technology) ;
- Chung, Yeon-Bok (College of Pharmacy. Chungbuk National University) ;
- Kwon, Oh-Seung (Loxicology Lab., Korea Institute of Science and Technology)
- 발행 : 2002.10.01
초록
A simple. specific and sensitive method for the determination of cyclosporine A (CsA) in human serum has been developed by a high performance liquid chromatography/diode array detector (DAD) and applied to pharmacokinetic study of CsA. This method involves the use of solid phase extraction procedure following rapid protein precipitation with zinc sulphate from 1
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