Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.420.2-421
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- 2002
HPLC Determination of Loratadine in Human Plasma with UV Detection and Pharmacokinetics of Loratadine Following Oral Administration of Tablet Formulation in Human
- Cho, Eun-Sook (College of Pharmacy. Dongduk Women′s University) ;
- Chun, In-Koo (College of Pharmacy. Dongduk Women′s University)
- Published : 2002.10.01
Abstract
A validated UV determination of loratadine in human plasma was developed and the pharmacokinetic profiles of single dose of loratadine were determined in 8 healthy volunteers. Human serum samples (1.0 mL) spiked with known concentration of loratadine and 50 ng diazepam as an internal standard were alkalinized with 500
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