대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.408.2-409
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- 2002
Surfactant-free microspheres of poly($\alpha$ -caprolactone)/poly(ethylene glycol)/poly($\varepsilon$ -caprolactone) triblock copolymers as a novel protein carriers
- Sun, Sang-Wook (College of Pharmacy, Chosun University) ;
- Jeong, Young-Il (College of Pharmacy, Chosun University) ;
- Jung, Sun-Woong (College of Pharmacy, Chosun University) ;
- Kim, Sung-Ho (College of Pharmacy, Chosun University)
- 발행 : 2002.10.01
초록
The aim of this study is to prepare biodegradable microspheres without use of any kind of surfactants or emulsifiers for a novel sustained delivery carriers of protein drugs. Poly(e-caprolactone)/poly(ethylene glycol)/poly(e-caprolactone) (CEC) triblock copolymer was synthesized by ring-opening of e-caprolactone with dihydroxy poly(ethylene glycol) and was used to make surfactant-free microspheres. (omitted)
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