Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.402.3-403
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- 2002
Chromatographic Analysis of Cilostazol in Human Plasma
- Park, Young-Joon (College of Pharmacy. Seoul National University) ;
- Park, Kyung-Mi (College of Pharmacy. Seoul National University) ;
- Ban, Eun-Mi (College of Pharmacy. Seoul National University) ;
- Chun, Soo-Kyung (College of Pharmacy. Seoul National University) ;
- Kim, Yang-Bae (College of Pharmacy. Seoul National University) ;
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Kim, Chong-Kook
(College of Pharmacy. Seoul National University)
- Published : 2002.10.01
Abstract
Cilostazol. a quinolinone derivative that inhibits phosphodiesterase. is used for the treatment of intermittent claudication resulting from peripheral arterial disease. In order to perform pharmacological and pharmacokinetic studies of cilostazol, specific. sensitive and reproducible analysis methods are demanded. Therefore. in the present study. an analytical method of cilostazol in human plasma was developed using semi-microbore HPLC equipped with automated column switching system. (omitted)
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