Chiral discrimination studies of (+)-(18-crown-6)-2.3.11.12-tetracarboxylic acid by NMR spectroscopy

  • Published : 2002.10.01

Abstract

The chiral stationary phase derived from (+) (18-crown-6)-2.3, 11.12-tetracarboxylic acid (18-C-6- TA) as a chiral selector has been employed for resolution of several $\alpha$-amino acids in HPLC. In a quest for the origin of chiral recognition of $\alpha$-amino acids in the presence of 18-C-6- T, A, as a chiral selector, these interactions responsible for the differential affinities shown toward enantioners were investigated by NNR spectroscopy. (omitted)

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