Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.394.2-394.2
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- 2002
Quantitative determination of pseudoephedrine in human plasma by reversed-phase liquid chromatography-electrospray ionization mass spectrometry
- Kim, Jin-Ki (College of Pharmacy Seoul National University) ;
- Cho, Jung-Hye (College of Pharmacy Seoul National University) ;
- Woo, Jong-Soo (Central Research Institute Hanmi Pharm Co., Ltd) ;
- Kim, Chong-Kook (College of Pharmacy Seoul National University)
- Published : 2002.10.01
Abstract
A sensitive and selective reversed-phase LC-ESI-MS method to quantitate pseudoephedrine in human plasma was developed and validated. Phenacetin was used as an internal standard. Samples were prepared simply by acetonitrile precipitation without an evaporation step. Chromatographic separation was achieved on a XTerra MS C18 column (
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