Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Regulation of the absorption of dietary sugar by $\alpha$-glucosidase inhibitors from herbal medicines

  • Yun, Yun-Ha (College of pharmacy Sahmyook University, Seoul, 139-742) ;
  • Lee, Shin-Seok (College of pharmacy Sahmyook University, Seoul, 139-742) ;
  • Chung, Nam-Yong (College of pharmacy Sahmyook University, Seoul, 139-742) ;
  • Yim, Dong-Sool (College of pharmacy Sahmyook University, Seoul, 139-742) ;
  • Lee, Sook-Yeon (College of pharmacy Sahmyook University, Seoul, 139-742) ;
  • Ha, Nam-Joo (College of pharmacy Sahmyook University, Seoul, 139-742) ;
  • Kim, Kyung-Jae (College of pharmacy Sahmyook University, Seoul, 139-742)
  • Published : 2002.10.01
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Abstract

The inhibitory activity of several crude drugs on $\alpha$-glucosidase, which are the key enzyme for carbohydrate digestion and the prevention of diabetic complications. was investigated. This experiment was designed to examine the hypoglycaemic effect of four water extracts crude drugs. We found two drugs. Mori radicis Cortex and Cudraniae radicis Cortex in several crude drugs remarkably inhibited $\alpha$-glucosidase. Two crude drugs were examined in streptozotocin induced high blood glucose mice. (omitted)

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