대한약학회:학술대회논문집 (Proceedings of the PSK Conference)

대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

In vitro Antiinflammatory Activity of the Essential oil Extracted from Chrysanthemum sibiricum in Murine Macrophage RAW 264.7 Cells

  • Lee, Kyung-Tae (College of Pharmacy. Kyung-Hee University, seoul 130-701) ;
  • Kim, Pyung-Kyu (College of Pharmacy. Kyung-Hee University, seoul 130-701) ;
  • Ji, Sa-Young (College of Pharmacy. Kyung-Hee University, seoul 130-701) ;
  • Shin, Kyoung-Min (College of Pharmacy. Kyung-Hee University, seoul 130-701) ;
  • Park, Jong-Won (College of Pharmacy. Kyungsung University,Pusan 608-736) ;
  • Jung, Hyun-Ju (College of Pharmacy. Kyungsung University,Pusan 608-736) ;
  • Park, Hee-Juhn (Division of Applied Plant Sciences sangJi Universit, Wonju 220-702)
  • 발행 : 2002.10.01
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초록

This research was undertaken to find the in vitro anti-inflammatory action of the essenetial oil (CS-oil) extracted from Chrysanthemum sibiricum (Compositae) herbs. We investigated the effects of the CS-oil not only on the formation NO and $PGE_2$ and TNF-$\alpha$ but also on inducible nitric oxide synthase and cyclooxygenase-2 (COX-2) in lipopolysaccharide (LPS)-induced murine macrophage 264.7. The data obtained were consistent with the modulation of iNOS enzyme expression. (omitted)

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