대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.383.3-384
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- 2002
Tyrosinase Inhibiting and DPPH Radical Scavenging Activities of Rosmarinic Acid and Its Methyl ester from Salvia miltiorrhiza
- Kang, Hye-Sook (Faculty of Food Science and Biotechnology Pukyong National University) ;
- Kim, Hyeung-Rak (Faculty of Food Science and Biotechnology Pukyong National University) ;
- Chung, Hae-Young (College of Pharmacy, Research Institute of Drug Development, Pusan National University) ;
- Choi, Jae-Sue (Faculty of Food Science and Biotechnology Pukyong National University)
- 발행 : 2002.10.01
초록
Rosmarinic acid (1) and methyl rosmarinic acid (2), isolated from the ethyl acetate soluble fraction of the methanolic extract of Salvia miltiorrhiza Bunge (Lamiaceae) were found to be the tyrosinase inhibitors and scavengers of 1, 1-diphenyl-2-picrylhydrzyl (DPPH) radical. Compounds 1 and 2 inhibited the oxidation of L-tyrosine catalyzed by mushroom tyrosinase with
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