Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Structure-Activity Relationship of Oleanane Disaccharides isolated from Akebia quinata on Both Cytotoxicity against Cancer Cells and NO inhibition against LPS-induced Macrophage 264.7

  • Jung, Hyun-Ju (Division of Applied Plant Sciences, Sangji University) ;
  • Lee, Jung-Ok (Pharmaceutical Screening Center Korea Research Institute of Chemical Technolog) ;
  • Lee, Kyung-Tae (College of Pharmacy, KyungHee University) ;
  • Choi, Jong-Won (College of Pharmacy, KyungSung University) ;
  • Park, Hee-Juhn (Division of Applied Plant Sciences, Sangji University)
  • Published : 2002.10.01
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Abstract

We have reported cytotoxicities based on several types of sugar linkage in saponins in addition to antitumor and antiinflammatory effects. In order to find further structure-activity relationship on the cytotoxicity of saponins. we intended to isolate oleanane disaccharides Irom the saponin-containing extract of Akebia Quinata (Lardizabalaceae). (omitted)

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