Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Antimicrobial effects of ocotillone isolated from the stem bark of Ailanthus altisshima

  • Lee, Dong-Gun (Research Center of Proteineous Materials, Chosun University) ;
  • Chang, Young-Su (College of Pharmacy, Chosun University) ;
  • Park, Yoon-Kyung (Research Center of Proteineous Materials, Chosun University, Kwang-ju 501-759, South Korea) ;
  • Hahm, Kyung-Soo (Research Center of Proteineous Materials, Chosun University, Kwang-ju 501-759, South Korea) ;
  • Hee, Moon-Young (Research Center of Proteineous Materials, Chosun University, Kwang-ju 501-759, South Korea) ;
  • Woo, Eun-Rhan (Research Center of Proteineous Materials, Chosun University, Kwang-ju 501-759, South Korea)
  • Published : 2002.10.01
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Abstract

Bioassay-directed chromatographic fractionation of a methylene chloride extract of Ailanthus altisshima indicated the presence of 20(S). 24(R), epoxy-25-hydroxydammarane-3-one(compound 1. ocotillone). which was isolated from this plant for the first time. Antimicrobial activity of compound 1 was measured by its degree of growth inhibition against bacterial and fungal cells and by a hemolytic assay with human erythrocytes, respectively. (omitted)

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