Three Cytotoxic compounds isolated from the seeds of Pharbitis nil

  • Lee, J.E. (College of Pharmacy. Catholic University of Daegu) ;
  • Byun, S.J. (College of Pharmacy. Catholic University of Daeg) ;
  • Son, J.K. (College of Pharmacy. Yeungnam University) ;
  • Lee, J.S. (Biochemistry, College of Science. Yeungnam University) ;
  • Lee, S.H. (College of Pharmacy. Yeungnam University) ;
  • Woo, M.H. (College of Pharmacy. Catholic University of Daegu)
  • Published : 2002.10.01

Abstract

Pharbitis nil Choisy (convolvulaceae) is an annual vine plant and grows at the wayside of Korea. Japan. China and India. The seeds of blue or red Pharbitis nil Choisy. Pharbitidis Semen, is black or red-brown. This seeds have been used as a purgative. From a preliminary experiment. Pharbitidis Semen exhibited anti-cancer activity. MeOH extract of this seeds was subsequently fractionated into four parts: methylene chloride, ethylacetate, n-butanol and water fractions. (omitted)

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