A convenient synthesis of 2′ or 3′-amino-2′(or 3′)-deoxyadenosine and 5′-chloro-2′(or 3′)-amino-deoxyadenosine analogues

  • Kim, Beom-Tae (Department of Chemistry and Research Center of Bioactive Materials, College of Natural Science, Chonbuk National University) ;
  • Kim, Seung-Ki (Department of Chemistry and Research Center of Bioactive Materials, College of Natural Science, Chonbuk National University) ;
  • Hwang, Ki-Jun (Department of Chemistry and Research Center of Bioactive Materials, College of Natural Science, Chonbuk National University)
  • Published : 2002.10.01

Abstract

New and improved preparations of structurally modified nucleosides are important goals in synthetic organic chemistry because of the potential utility of these compounds as synthetic precursors of many biologically active molecules in cells. In our program to synthesize the bioactive nucleosides, such as AdoHcy hydrolase inhibitors and cyclic adenosine diphosphoribose(cADPR) analogues. (omitted)

Keywords