Straightforward synthesis of 4'${\alpha}$-C-hydroxymethyl branched novel carbocyclic nucleosides

  • 발행 : 2002.10.01

초록

Carbocyclic nucleosides are unique class in which a methylene group replaces the oxygen in the furan, which result in metabolic stability to endogenous phosphorylase. The biologically active natural carbocyclic nucleosides such as aristeromycin and neplanocin were found to possess interesting biological properties including antiviral and antitumor activity. (omitted)

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