대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
- /
- Pages.336.1-336.1
- /
- 2002
Mn$2^+$ dependent ClpL ATPase in Streptococcus pneumoniae
- Park, Moo-Hyun (College of Pharmacy. Sungkyunkwan University) ;
- Kwon, Hyog-Young (College of Pharmacy. Sungkyunkwan University) ;
- Jung, Seung-Ha (College of Pharmacy. Sungkyunkwan University) ;
- Pyo, Suhk-Neung (College of Pharmacy. Sungkyunkwan University) ;
- Rhee, Dong-Kwon (College of Pharmacy. Sungkyunkwan University)
- 발행 : 2002.10.01
초록
HSP100/Clp family functions as molecular chaperone and ATP dependent protease. The Streptococcus pneumoniae ClpL. a homologue of bacterial ClpB and yeast cytosolic HSP 104. is one of major heat shock proteins but its biochemical properties are unknown. In this study. ClpL in Streptococcus pneumoniaewas characterized using histidine tagged recombinant ClpL. When ATP hydrolysis activity was compared in the presence or absence of a variety of nucleotides or divalent ions. either ATP or Mn
키워드