Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.316.3-317
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- 2002
Induction of Differentiation in HI-60 Human leukemia cells by Acteoside.
- Lee, Kyung-Won (College of Pharmacy, Kyung Hee University) ;
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Choi, jung-Hye
(College of Pharmacy, Kyung Hee University) ;
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Lee, kyung-Tae
(College of Pharmacy, Kyung Hee University) ;
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Lee, yong-Sup
(Division of Life Sciences, Korea Institute of Science and Technology) ;
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Kim, hyoung-Ja
(Division of Life Sciences, Korea Institute of Science and Technology) ;
- Pak , Hee-Juhn (Division of Applid Science, Sanji University)
- Published : 2002.10.01
Abstract
In previous reports, we exhibited that acteoside showed significant cytotoxicity against various cancer cells. In this study we investigated that acteoside is capable of inducing differentiation in HL -60 human leukemia cell line. After being treated with acteoside, the growth curve was decreased remakably in a dose- and time-dependent manner, and cell doubling time was delayed. Exposure of cells to 20
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