대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.309.2-309.2
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- 2002
Expression and Characterization of Escherichia coli Adhesin Protein Linked to Cholera Toxin A2/B Subunits in Escherichia coli
- Lee, Young-Hwa (College of Pharmacy, Sungkyunkwan University) ;
- Ryu, Dong-Kyun (College of Pharmacy, Sungkyunkwan University) ;
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Rhee, Dong-Kwon
(College of Pharmacy, Sungkyunkwan University)
;
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Pyo, Suhk-Neung
(College of Pharmacy, Sungkyunkwan University)
- 발행 : 2002.10.01
초록
The FimH subunit of type l-fimbriated Escherichia coli has been determined as a major cause of urinary tract infection. To produce a possible vaccine antigen against urinary tract infection, the fimH gene was genetically coupled to the ctxa2b gene, which was then cloned into pMAL -p2E expression vector. The chimaeric construction of pMALfimH/ctxa2b was transformed into Escherichia coli TB1 and its N-terminal amino acid sequence was analyzed. (omitted)
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