대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.305.1-305.1
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- 2002
Microglial activation and tyrosine hydroxylase immunoreactivity in the substantia nigral region following transient focal ischemia in rats
- Jung, Ji-Wook (Department of Oriental Pharmaceutical Science, college of Pharmacy, Kyung Hee University) ;
- Oh, Jin-Kyung (Department of Oriental Pharmaceutical Science, college of Pharmacy, Kyung Hee University) ;
- Huh , Young-Buhm (Department of Anatomy, College of Medicine, Kyung Hee University) ;
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Ryu, Jong-Hoon
(Department of Oriental Pharmaceutical Science, college of Pharmacy, Kyung Hee University)
- 발행 : 2002.10.01
초록
The temporal profiles of the changes of dopaminergic cell and microglial activation induced by transient cerebral ischemia was investigated in the substantia nigral region which lay outside ischemic areas of rat brain after middle cerebral artery occlusion (MCAO). Transient cerebral ischemia was induced by intraluminal occlusion of the right middle cerebral artery for 2 hand reperfusion was continued for 1, 2. 3. 7. 10. 14. 30, 60. and 120 days. Activated microglial cells were visualized with immunohistochmistry using OX-43 antibody. (omitted)
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