Neuroprotective effect of woganin in a rodent model of permanent focal cerebral ischemia

  • Cho , Jung-Sook (Department of Pharmacology, College of Medicine, Dongguk University) ;
  • Lee, Hyung-Kyu (Korea Research Institute of Bioscience and Biotechnology)
  • Published : 2002.10.01

Abstract

Wogonin. a flavonoid originated from the root of Scutellaria baicalensis Georgi. is known to exhibit potent anti-inflammatory effects and variable degrees of antioxidant and free radical scavenging effects depending on the experimental systems. In addition. wogonin has been reported to protect neurons from excitotoxic and oxidative injuries in primary cultured rat cortical cells. (omitted)

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