Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Adenosine inhibits the death in immunostimulated murine astrocytes deprived of glucose

  • Choi, Min-Sik (Department of Pharmacology, College of Pharmacy, Seoul National University) ;
  • Chang, Eun-Sook (Department of Pharmacology, College of Pharmacy, Seoul National University) ;
  • Park, Ji-Woong (Department of Pharmacology, College of Pharmacy, Seoul National University) ;
  • Yoo, Byung-Kwon (Department of Pharmacology, College of Pharmacy, Seoul National University) ;
  • Park, Gyu-Hwan (Department of Pharmacology, College of Pharmacy, Seoul National University) ;
  • Lee, Woo-Jong (Department of Pharmacology, College of Pharmacy, Seoul National University) ;
  • Yoon, Suh-Young (Department of Pharmacology, College of Pharmacy, Seoul National University) ;
  • Ko, Kwang-Ho (Department of Pharmacology, College of Pharmacy, Seoul National University)
  • Published : 2002.10.01
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Abstract

Adenosine has been associated with protection of neurons from noxious stimuli both by receplor- and non receptor-mediated mechanisms. Previously we have reported that immunostimulated astrocytes were highly vulnerable to glucose deprivation. In the present study we investigated the effect of adenosine and related nucleotides on the susceptibility of immunostimulated astrocytes to glucose deprivation. (omitted)

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