대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.299.1-299.1
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- 2002
Role of Kupffer Cells in Alteration of Vasoregulatory Gene Expression in Hepatic Ischemia/Reperfusion
- Kim, Yong-Hyuk (College of Pharmacy, Sungkyunkwan University) ;
- Kim, Sung-Ho (College of Pharmacy, Sungkyunkwan University) ;
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Lee, Sun-Mee
(College of Pharmacy, Sungkyunkwan University)
- 발행 : 2002.10.01
초록
Failure of the hepatic microcirculation is a major component of reperfusion injury in the liver. However. the vasoactive mediators involved in the regulation of sinusoidal flow during reperfusion following hepatic ischemia remain to be identified. We investigate the role of Kupffer cells in hepatic ischemia/reperfusion (l/R)-induced imbalance of vasoregulatory gene expression. Rats were subjected to 60 min hepatic ischemia, followed by 5 h of reperfusion. (omitted)
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