대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.284.1-284.1
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- 2002
In vitro mutagenicity and genotoxicity study of PAHs and nitro-PAHs using the bacterial revertant (Ames) test and alkaline single cell gel electrophorosis (Comet) assay
- Kim, Soung-Ho (Environmental Toxicology and Health Science, College of Pharmacy, Sungkyunkwan University,Suwon City, Kyunggi-Do 440-746 Korea) ;
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Oh, Seung-Min
(Environmental Toxicology and Health Science, College of Pharmacy, Sungkyunkwan University,Suwon City, Kyunggi-Do 440-746 Korea) ;
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Chung, Kyu-Hyuck
(Environmental Toxicology and Health Science, College of Pharmacy, Sungkyunkwan University,Suwon City, Kyunggi-Do 440-746 Korea)
- 발행 : 2002.10.01
초록
In previous studies, we demonstrated that ambient PM collected from urban site of Korea air could induce DNA damage, Various mutagens and carcinogens present in the urban air differ according to the source of the pollutants. Polycyclic aromatic hydrocarbons (PAHs) and their nitrated compound are produced in the combustion of fossil fuels as diesel emission exhausts. In recent, PAH and nitro-PAH have been identified in urban air particulate matter (PM). and some of them were found to be tumorigenic in experimental animals and humans. (omitted)
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