Action of lysophosphatidylcholine in U937 human monocytes

  • Yun, Mi-Ran (Laboratory of Pharmacology. College of Pharmacy. Pusan National University) ;
  • Im, Dong-Soon (Laboratory of Pharmacology. College of Pharmacy. Pusan National University)
  • Published : 2002.10.01

Abstract

Atherosclerosis is a main cause of cardiovascular diseases (that is angina. hypertension. cardiac infarction) and stroke. High level of low-density lipoproteins (LDL) in blood has been implicated as an important factor of atherosclerosis progression. Recently researches in endothelial cells unveiled the roles of Iysophosphatidylcholine (LPC). a constituent of oxidized LDL in atherosclerosis. (omitted)

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