Assessment of allergenicity of genetically modified foods (GMOs)

  • Lee, Jung-Hyun (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Yoon, Won-Ki (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Han, Sang-Bae (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Yun, Si-On (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Park, Sun-Hong (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Lee, Hyun-Ju (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Yoon, Pyung-Seop (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Moon, Jae-Sun (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Kim, Hyung-Chin (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
  • Kim, Hwan-Mook (Biopotency Evaluation Laboratory, Korea Research Institute of Bioscience Biotechnology(KRIBB))
  • Published : 2002.10.01

Abstract

The potential allergenicity of the transgene products in genetically modified organisms (GMOs). has been an important issue. As a part of the risk assessment of GMOs. we investigated the physicochemical stability and the immunogenicity of food allergens to determine their allergenicity. We have systematically evaluated the stability of food allergens in the gastrointestinal tract by using simple models of gastric (Stimulated gastric fluid) and intestinal (Stimulated intestinal fluid) digestion. (omitted)

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