대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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- Pages.259.1-259.1
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- 2002
Immunomodulatory activity of a polysaccharide isolated from cell culture of Acantopanax senticosus
- Ahn, Hyo-Jung (Biopotency Evaluation Laboratory) ;
- Han, Sang-Bae (Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
- Yoon, Yeo-Dae (Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
- Lee, Haeng-Soon (Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
- Moon, Jae-Sun (Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
- Lee, Chang-Woo (Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
- Lee, Ki-Hoon (Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
- Park, Song-Kyu (Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
- Kim, Hyung-Chin (Korea Research Institute of Bioscience Biotechnology(KRIBB)) ;
- Kim, Hwan-Mook (Korea Research Institute of Bioscience Biotechnology(KRIBB))
- 발행 : 2002.10.01
초록
Many polysaccharides isolated from plants are considered to be biological response modifiers and have been shown to enhance various immune responses in vivo and in vitro. Here we demonstrate that a polysaccharide isolated from cell culture of Acanthopanax senticosus (AS) has a unique mode of immunostimulation with regard to its cell-type specificity. AS was found to markedly increase polyclonal IgM antibody production and the proliferation of B cells. and to activate iNOS transcription and NO production in macrophages. (omitted)
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